BIOKIT, 2025 PROD 00025

Enzymes are highly efficient, specific, selective, biodegradable, and non-toxic, allowing them to function effectively under mild biological conditions. These characteristics make enzymes a sustainable and eco-friendly alternative to traditional catalysts in industrial applications. However, leveraging enzymes for industrial use often requires extensive and costly experimental engineering. While computational methods offer promising solutions, they have yet to demonstrate the capability to rapidly design highly efficient enzymes that rival those found in nature. Unlike conventional approaches, our computational method—developed in the previous ERC-STG—introduces both active site and distal mutations to modulate enzyme conformational dynamics, achieving catalytic efficiency improvements of up to 1000-fold. This project aims to leverage the proprietary technology from ERC-STG and ERC-POC to develop a series of patentable, rationally designed enzyme kits specializing in stereoselective carbon-carbon bond formation. The ultimate goal is to establish a spin-off company to commercialize both the enzyme kits and the proprietary enzyme optimization technology. These innovations will serve as the foundation of the project, offering industries a cost-effective, scalable, and environmentally sustainable solution.